Publications

Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile
Heidemarie Rossiter  1 , Dragan Copic  2 , Martin Direder  2 , Florian Gruber  1 , Samuele Zoratto  3 , Martina Marchetti-Deschmann  3 , Christopher Kremslehner  1 , Michaela Sochorová  1 , Ionela-Mariana Nagelreiter  1   4 , Veronika Mlitz  1 , Maria Buchberger  1 , Barbara Lengauer  1 , Bahar Golabi  1 , Supawadee Sukseree  1 , Michael Mildner  1 , Leopold Eckhart  1 , Erwin Tschachler  Autophagy, 2021 Sep 7;1-15.Online ahead of print.
PMID: 34491140

APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans.
Tsiantoulas D, Eslami M, Obermayer G, Clement M, Smeets D, Mayer FJ, Kiss MG, Enders L, Weißer J, Göderle L, Lambert J, Frommlet F, Mueller A, Hendrikx T, Ozsvar-Kozma M, Porsch F, Willen L, Afonyushkin T, Murphy JE, Fogelstrand P, Donzé O, Pasterkamp G, Hoke M, Kubicek S, Jørgensen HF, Danchin N, Simon T, Scharnagl H, März W, Borén J, Hess H, Mallat Z, Schneider P, Binder CJ.
Nature, 2021 Sep; 597(7874):92-96.
PMID: 34433968

Adipose Stem Cell-Derived Extracellular Vesicles Induce Proliferation of Schwann Cells via Internalization
Maximilian Haertinger, Tamara Weiss, Anda Mann, Annette Tabi, Victoria Brandel, and Christine Radtke
Cells. 2020 Jan; 9(1): 163. Published online 2020 Jan 9
PMID: 31936601

Cell death induced autophagy contributes to terminal differentiation of skin and skin appendages.
Koenig U, Robenek H, Barresi C, Brandstetter M, Resch GP, Gröger M, Pap T, Hartmann C.
Autophagy. 2019 Aug 4:1-14. doi: 10.1080/15548627.2019.1646552. [Epub ahead of print]
PMID: 31379249

The FAK inhibitor BI 853520 inhibits spheroid formation and orthotopic tumor growth in malignant pleural mesothelioma.
Laszlo V, Valko Z, Ozsvar J, Kovacs I, Garay T, Hoda MA, Klikovits T, Stockhammer P, Aigner C, Gröger M, Klepetko W, Berger W, Grusch M, Tovari J, Waizenegger IC, Dome B, Hegedus B.
J Mol Med (Berl). 2019 Feb; 97(2):231-242.
PMID: 30539198

Neutrophil-Mediated Proteolysis of Thrombospondin-1 Promotes Platelet Adhesion and String Formation.
Seif K, Alidzanovic L, Tischler B, Ibrahim N, Zagrapan B, Rauscher S, Salzmann M, Hell L, Mauracher LM, Budde U, Schmid JA, Jilma B, Pabinger I, Assinger A, Starlinger P, Brostjan C.
Thromb Haemost. 2018 Dec;118(12):2074-2085. doi: 10.1055/s-0038-1675229. Epub 2018 Nov 12.
PMID: 30419595

Inactivation of autophagy leads to changes in sebaceous gland morphology and function.
Rossiter H, Stübiger G, Gröger M, König U, Gruber F, Sukseree S, Mlitz V, Buchberger M, Oskolkova O, Bochkov V, Eckhart L, Tschachler E.
Exp Dermatol. 2018 Oct; 27(10):1142-1151.
PMID: 30033522

Nintedanib Is Active in Malignant Pleural Mesothelioma Cell Models and Inhibits Angiogenesis and Tumor Growth In Vivo.
Laszlo V, Valko Z, Kovacs I, Ozsvar J, Hoda MA, Klikovits T, Lakatos D, Czirok A, Garay T, Stiglbauer A, Helbich TH, Gröger M, Tovari J, Klepetko W, Pirker C, Grusch M, Berger W, Hilberg F, Hegedus B, Dome B.
Clin Cancer Res. 2018 Aug 1; 24(15):3729-3740.
PMID: 29724868

CXCL5 facilitates melanoma cell-neutrophil interaction and lymph node metastasis.
Soler-Cardona A, Forsthuber A, Lipp K, Ebersberger S, Heinz M, Schossleitner K, Buchberger E, Gröger M, Petzelbauer P, Hoeller C, Wagner E, Loewe R.
J Invest Dermatol. 2018 Feb 20. pii: S0022-202X(18)30125-8 [Epub ahead of print]
PMID:29474942

Exploring Metabolic Configurations of Single Cells within Complex Tissue Microenvironments.
Miller A, Nagy C, Knapp B, Laengle J, Ponweiser E, Groeger M, Starkl P, Bergmann M, Wagner O, Haschemi A.
Cell Metab. 2017 Nov 7;26(5):788-800. Epub 2017 Sep 7.
PMID:28889950

Oncolytic influenza A virus expressing interleukin-15 decreases tumor growth in vivo.
Hock K, Laengle J, Kuznetsova I, Egorov A, Hegedus B, Dome B, Wekerle T, Sachet M, Bergmann M.
Surgery. 2017 Mar;161(3):735-746. doi: 10.1016/j.surg.2016.08.045. Epub 2016 Oct 21.
PMID:27776794

IL-33 stimulates the release of procoagulant microvesicles from human monocytes and differentially increases tissue factor in human monocyte subsets.
Stojkovic S, Thulin Å, Hell L, Thaler B, Rauscher S, Baumgartner J, Gröger M, Ay C, Demyanets S, Neumayer C, Huk I, Spittler A, Huber K, Wojta J, Siegbahn A, Åberg M.
Thromb Haemost. 2017 May 11. doi: 10.1160/TH16-10-0784. [Epub ahead of print]
PMID: 28492698 [PubMed - as supplied by publisher]

A Rapid Automated Protocol for Muscle Fiber Population Analysis in Rat Muscle Cross Sections Using Myosin Heavy Chain Immunohistochemistry.
Bergmeister KD, Gröger M, Aman M, Willensdorfer A, Manzano-Szalai K, Salminger S, Aszmann OC.
J Vis Exp. 2017 Mar 28;(121). doi: 10.3791/55441.
PMID: 28448058 [PubMed - in process]

Does Extracellular DNA Production Vary in Staphylococcal Biofilms Isolated From Infected Implants versus Controls?
Zatorska B, Groger M, Moser D, Diab-Elschahawi M, Lusignani LS, Presterl E.
Clin Orthop Relat Res. 2017 Feb 13. doi: 10.1007/s11999-017-5266-0.
[Epub ahead of print]
PMID: 28194715 [PubMed - as supplied by publisher]

HO-1 inhibits preadipocyte proliferation and differentiation at the onset of obesity via ROS dependent activation of Akt2.
Wagner G, Lindroos-Christensen J, Einwallner E, Husa J, Zapf TC, Lipp K, Rauscher S, Gröger M, Spittler A, Loewe R, Gruber F, Duvigneau JC, Mohr T, Sutterlüty-Fall H, Klinglmüller F, Prager G, Huppertz B, Yun J, Wagner O, Esterbauer H, Bilban M.
Sci Rep. 2017 Jan 19;7:40881. doi: 10.1038/srep40881.
PMID: 28102348 [PubMed - in process]Free PMC Article

Inhibition of the transcriptional repressor complex Bcl-6/BCoR induces endothelial sprouting but does not promote tumor growth.
Buchberger E, Payrhuber D, El Harchi M, Zagrapan B, Scheuba K, Zommer A, Bugyik E, Dome B, Kral JB, Schrottmaier WC, Schabbauer G, Petzelbauer P, Gröger M, Bilban M, Brostjan C.
Oncotarget. 2017 Jan 3;8(1):552-564. doi: 10.18632/oncotarget.13477.
PMID: 27880939 [PubMed - in process]Free PMC Article

Polystyrene-Divinylbenzene-Based Adsorbents Reduce Endothelial Activation and Monocyte Adhesion Under Septic Conditions in a Pore Size-Dependent Manner.
Eichhorn T, Rauscher S, Hammer C, Gröger M, Fischer MB, Weber V.
Inflammation. 2016 Oct;39(5):1737-46. doi: 10.1007/s10753-016-0408-1.
PMID: 27503310 [PubMed - indexed for MEDLINE]Free PMC Article

 Polarization properties of single layers in the posterior eyes of mice and rats investigated using high resolution polarization sensitive optical coherence tomography.
Fialová S, Augustin M, Glösmann M, Himmel T, Rauscher S, Gröger M, Pircher M, Hitzenberger CK, Baumann B.
Biomed Opt Express. 2016 Mar 24;7(4):1479-95. doi: 10.1364/BOE.7.001479. eCollection 2016 Apr 1.
PMID: 27446670 [PubMed]Free PMC Article

 Interleukin-33 stimulates GM-CSF and M-CSF production by human endothelial cells.
Montanari E, Stojkovic S, Kaun C, Lemberger CE, de Martin R, Rauscher S, Gröger M, Maurer G, Neumayer C, Huk I, Huber K, Demyanets S, Wojta J.
Thromb Haemost. 2016 Aug 1;116(2):317-27. doi: 10.1160/TH15-12-0917. Epub 2016 May 12.
PMID: 27173404 [PubMed - in process]

Tissue factor is induced by interleukin-33 in human endothelial cells: a new link between coagulation and inflammation.
Stojkovic S, Kaun C, Basilio J, Rauscher S, Hell L, Krychtiuk KA, Bonstingl C, de Martin R, Gröger M, Ay C, Holnthoner W, Eppel W, Neumayer C, Huk I, Huber K, Demyanets S, Wojta J.
Sci Rep. 2016 May 4;6:25171. doi: 10.1038/srep25171.
PMID: 27142573 [PubMed - in process]Free PMC Article

Evidence That Cingulin Regulates Endothelial Barrier Function In Vitro and In Vivo.
Schossleitner K, Rauscher S, Gröger M, Friedl HP, Finsterwalder R, Habertheuer A, Sibilia M, Brostjan C, Födinger D, Citi S, Petzelbauer P.
Arterioscler Thromb Vasc Biol. 2016 Apr;36(4):647-54. Epub 2016 Jan 28. PMID: 26821949

Neutrophil Gelatinase-Associated Lipocalin (NGAL) is Associated with Symptomatic Carotid Atherosclerosis and Drives Pro-inflammatory State In Vitro.
Eilenberg W, Stojkovic S, Piechota-Polanczyk A, Kaun C, Rauscher S, Gröger M, Klinger M, Wojta J, Neumayer C, Huk I, Demyanets S.
Eur J Vasc Endovasc Surg. 2016 Feb 29. [Epub ahead of print] PMID:26947538

Automated muscle fiber type population analysis with ImageJ of whole rat muscles using rapid myosin heavy chain immunohistochemistry.
Bergmeister KD, Gröger M, Aman M, Willensdorfer A, Manzano-Szalai K, Salminger S, Aszmann OC.
Muscle Nerve. 2016 Jan 20.[Epub ahead of print] PMID:26788932

Spectral degree of polarization uniformity for polarization-sensitive OCT.
Baumann B, Zotter S, Pircher M, Götzinger E, Rauscher S, Glösmann M, Lammer J, Schmidt-Erfurth U, Gröger M, Hitzenberger CK.
J Mod Opt. 2015;62(21):1758-1763 PMID:2668982

Melanin Pigmentation in Rat Eyes: In Vivo Imaging by Polarization-Sensitive Optical Coherence Tomography and Comparison to Histology.
Baumann B, Schirmer J, Rauscher S, Fialová S, Glösmann M, Augustin M, Pircher M, Gröger M, Hitzenberger CK.
JInvest Ophthalmol Vis Sci. 2015. Nov 1;56(12):7462-72. PMID:2659606

Mouse hippocampal GABAB1 but not GABAB2 subunit-containing receptor complex levels are paralleling retrieval in the multiple-T-maze.
Falsafi SK, Ghafari M, Miklósi AG, Engidawork E, Gröger M, Höger H, Lubec G.
Front Behav Neurosci. 2015. Oct 19;9:276. eCollection 2015. PMID:26539091

Spatial and Working Memory Is Linked to Spine Density and Mushroom Spines.
Mahmmoud RR, Sase S, Aher YD, Sase A, Gröger M, Mokhtar M, Höger H, Lubec G.
PLoS One. 2015. Oct 15;10(10):e0139739. eCollection 2015. PMID:26469788

Molecular and biochemical characterization of Entamoeba histolytica fructokinase.
Matt J, Duchêne M..
Parasitol Res. 2015. May;114(5):1939-47. Epub 2015 Feb 21. PMID:25700717

Frontal cortex and hippocampus neurotransmitter receptor complex level parallels spatial memory performance in the radial arm maze.
Shanmugasundaram B, Sase A, Miklosi AG, Sialana FJ, Subramaniyan S, Aher YD, Gröger M, Höger H, Bennett KL, Lubec G.
Behav Brain Res. . Epub 2015 Apr 28. [Epub ahead of print] PMID:25930220

Individual phases of contextual fear conditioning differentially modulate dorsal and ventral hippocampal GluA1-3, GluN1-containing receptor complexes and subunits.
Sase S, Sase A, Sialana FJ Jr, Gröger M, Bennett KL, Stork O, Lubec G, Li L.
Hippocampus..2015 Apr 25. [Epub ahead of print] PMID:25914080

Drebrin depletion alters neurotransmitter-receptor levels in protein-complexes, dendritic spine morphogenesis and memory-related synaptic plasticity in the mouse hippocampus.
Jung G, Kim EJ, Cicvaric A, Sase S, Gröger M, Höger H, Sialana FJ, Berger J, Monje FJ, Lubec G.
J Neurochem. 2015 Apr 11. [Epub ahead of print] PMID:25865831

Hippocampal receptor complexes paralleling LTP reinforcement in the spatial memory holeboard test in the rat.
Subramaniyan S, Hajali V, Scherf T, Sase SJ, Sialana FJ, Gröger M, Bennett KL, Pollak A, Li L, Korz V, Lubec G.
Behav Brain Res. 2015 Apr 15; 283:162-74. Epub 2015 Jan 30. PMID: 25639541

Autophagy facilitates secretion and protects against degeneration of the Harderian gland.
Koenig U, Fobker M, Lengauer B, Brandstetter M, Resch GP, Gröger M, Plenz G, Pammer J, Barresi C, Hartmann C, Rossiter H.
Autophagy. 2015 Feb;11(2):298-313. PMID:25484081

Peripapillary rat sclera investigated in vivo with polarization-sensitive optical coherence tomography.
Baumann B, Rauscher S, Glösmann M, Götzinger E, Pircher M, Fialová S, Gröger M, Hitzenberger CK.
Invest Ophthalmol Vis Sci. 2014 Oct 28;55(11):7686-96. PMID:25352116

Monocytes with angiogenic potential are selectively induced by liver resection and accumulate near the site of liver regeneration.
Schauer D, Starlinger P, Zajc P, Alidzanovic L, Maier T, Buchberger E, Pop L, Gruenberger B, Gruenberger T, Brostjan C.
BMC Immunol. 2014. Oct 30;15:50. PMID:25359527

Dynamic O-Linked N-Acetylglucosamine Modification of Proteins Affects Stress Responses and Survival of Mesothelial Cells Exposed to Peritoneal Dialysis Fluids.
Herzog R, Bender TO, Vychytil A, Bialas K, Aufricht C, Kratochwill K.
J Am Soc Nephrol. 2014 May 22. [Epub ahead of print] PMID:24854264

Interleukin-33 induces urokinase in human endothelial cells – possible impact on angiogenesis.
Stojkovic S, Kaun C, Heinz M, Krychtiuk KA, Rauscher S, Lemberger CE, de Martin R, Gröger M, Petzelbauer P, Huk I, Huber K, Wojta J, Demyanets S.
J Thromb Haemost. 2014 Jun;12(6):948-57. PMID:24702774

Levosimendan exerts anti-inflammatory effects on cardiac myocytes and endothelial cells in vitro.
Krychtiuk KA, Watzke L, Kaun C, Buchberger E, Hofer-Warbinek R, Demyanets S, Pisoni J, Kastl SP, Rauscher S, Gröger M, Aliabadi A, Zuckermann A, Maurer G, de Martin R, Huber K, Wojta J, Speidl WS.
Thromb Haemost. 2014 Oct 2;113(1). PMID: 25273157

Protein kinases paralleling late-phase LTP formation in dorsal hippocampus in the rat.
Li L, Jia W, Sase S, Gröger M, Pollak A, Korz V, Lubec G.
Neurochem Int. 2014 Jun 6.S0197-0186(14)00136-3. PMID:24911953

Interleukin-33 induces urokinase in human endothelial cells-possible impact on angiogenesis.
Stojkovic S, Kaun C, Heinz M, Krychtiuk KA, Rauscher S, Lemberger CE, de Martin R, Gröger M, Petzelbauer P, Huk I, Huber K, Wojta J, Demyanets S.
J Thromb Haemost. 2014 Jun;12(6):948-57. PMID:24702774

Overexpression of the Transcriptional Repressor Complex BCL-6/BCoR Leads to Nuclear Aggregates Distinct from Classical Aggresomes.
Buchberger E, El Harchi M, Payrhuber D, Zommer A, Schauer D, Simonitsch-Klupp I, Bilban M, Brostjan C.
PLoS One. 2013 Oct 11;8(10):e76845. PMID:24146931 

GSK-3β inhibition protects mesothelial cells during experimental peritoneal dialysis through upregulation of the heat shock response.
Rusai K, Herzog R, Kuster L, Kratochwill K, Aufricht C.
Cell Stress Chaperones. 2013 Sep;18(5):569-79.
PMID:23494401

Essential role for mammalian apurinic/apyrimidinic (AP) endonuclease Ape1/Ref-1 in telomere maintenance. 
Madlener S, Ströbel T, Vose S, Saydam O, Price BD, Demple B, Saydam N.
Proc Natl Acad Sci U S A. 2013 Oct 14. [Epub ahead of print] PMID:23823477

Human but not mouse adipogenesis is critically dependent on LMO3. 
Lindroos J, Husa J, Mitterer G, Haschemi A, Rauscher S, Haas R, Gröger M, Loewe R, Kohrgruber N, Schrögendorfer KF, Prager G, Beck H, Pospisilik JA, Zeyda M, Stulnig TM, Patsch W, Wagner O, Esterbauer H, Bilban M.
Cell Metab. 2013 Jul 2; 18(1):62-74 PMID:23823477

Oncostatin M is a FIP1L1/PDGFRA-dependent mediator of cytokine production in chronic eosinophilic leukemia. 
Hoermann G, Cerny-Reiterer S, Sadovnik I, Müllauer L, Bilban M, Gröger M, Horny HP, Reiter A, Schmitt-Graeff A, Mannhalter C, Valent P, Mayerhofer
M.Allergy. 2013 Jun;68(6):713-23. doi: 10.1111/all.12139. Epub 2013 Apr 27. PMID:23621172

Components of the interleukin-33/ST2 system are differentially expressed and regulated in human cardiac cells and in cells of the cardiac vasculature. 
Demyanets S, Kaun C, Pentz R, Krychtiuk KA, Rauscher S, Pfaffenberger S, Zuckermann A, Aliabadi A, Gröger M, Maurer G, Huber K, Wojta J.
J Mol Cell Cardiol. 2013 Apr 6; 60C:16-26. doi: 10.1016/j.yjmcc.2013.03.020. [Epub ahead of print] PMID:23567618

Thymoquinone attenuates tumor growth in ApcMin mice by interference with Wnt-signaling. 
Lang M, Borgmann M, Oberhuber G, Evstatiev R, Jimenez K, Dammann KW, Jambrich M, Khare V, Campregher C, Ristl R, Gasche C.
Mol Cancer. 2013 May 13;12(1):41. doi: 10.1186/1476-4598-12-41. PMID:23668310

Epidermal growth factor facilitates melanoma lymph node metastasis by influencing tumor lymphangiogenesis. 
Bracher A, Cardona AS, Tauber S, Fink AM, Steiner A, Pehamberger H, Niederleithner H, Petzelbauer P, Gröger M, Loewe R.
J Invest Dermatol. 2013 Jan;133(1):230-8. doi: 10.1038/jid.2012.272. Epub 2012 Sep 6. PMID:22951723

Interleukin-33 induces expression of adhesion molecules and inflammatory activation in human endothelial cells and in human atherosclerotic plaques. 
Demyanets S, Konya V, Kastl SP, Kaun C, Rauscher S, Niessner A, Pentz R, Pfaffenberger S, Rychli K, Lemberger CE, de Martin R, Heinemann A, Huk I, Gröger M, Maurer G, Huber K, Wojta J.
Arterioscler Thromb Vasc Biol. 2011 Sep;31(9):2080-9. doi: 10.1161/ATVBAHA.111.231431. Epub 2011 Jul 7. PMID:21737781

Exercise training increases endothelial progenitor cells and decreases asymmetric dimethylarginine in peripheral arterial disease: a randomized controlled trial. 
Schlager O, Giurgea A, Schuhfried O, Seidinger D, Hammer A, Gröger M, Fialka-Moser V, Gschwandtner M, Koppensteiner R, Steiner S.
Atherosclerosis. 2011 Jul;217(1):240-8. doi: 10.1016/j.atherosclerosis.2011.03.018. Epub 2011 Apr 8. PMID:21481871

Identification of oncostatin M as a STAT5-dependent mediator of bone marrow remodeling in KIT D816V-positive systemic mastocytosis. 
Hoermann G, Cerny-Reiterer S, Perné A, Klauser M, Hoetzenecker K, Klein K, Müllauer L, Gröger M, Nijman SM, Klepetko W, Valent P, Mayerhofer M.
Am J Pathol. 2011 May;178(5):2344-56. doi: 10.1016/j.ajpath.2011.01.020. Epub 2011 Mar 31. PMID:21457934